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In a patient with Guillain-Barre syndrome, which result of bedside pulmonary function testing most strongly indicates the need for ventilatory assistance?

Forced expiratory volume (FEV1) equal to tidal volume

Vital capacity equal to tidal volume

A vital capacity equal to tidal volume is a significant indicator of respiratory compromise in a patient with Guillain-Barre syndrome. Vital capacity is the maximum amount of air a person can exhale after inhaling deeply, and it reflects the overall strength and endurance of respiratory muscles. In Guillain-Barre syndrome, where muscle weakness is a hallmark, a vital capacity that is equal to or low compared to tidal volume suggests that the patient has drastically reduced their ability to take in air, leading to inadequate ventilation. When vital capacity significantly drops, it raises concerns about respiratory failure, as the patient may not be able to breathe adequately on their own. Thus, this finding is a clear indication that the patient may need ventilatory assistance to support their breathing and prevent complications arising from hypoventilation or respiratory failure. This context highlights how critical it is to monitor lung function in patients with conditions like Guillain-Barre syndrome, where muscle weakness can rapidly progress.

Increased peak expiratory flow rate (PEFR)

Normal total lung capacity

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